other_material
confidence high
sentiment positive
materiality 0.85
Incannex reports positive Phase 2 results for IHL-42X in obstructive sleep apnea; AHI reduced up to 83%
Incannex Healthcare Inc.
- IHL-42X reduced AHI up to 83% (high-dose) and 79% (low-dose) from baseline; 41.2% of high-dose patients achieved >30% reduction.
- Statistically significant improvements in PGI-C sleep related impairment, fatigue, ODI, and patient-reported outcomes (FOSQ-10, ESS, PROMIS).
- No serious adverse events reported; treatment-emergent adverse effects infrequent, mostly mild/moderate.
- Preparing End-of-Phase 2 meeting with FDA; advancing toward commercial readiness and Phase 3 development.
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