secwatch.observer — SEC 8-K summary ====================================== Issuer: Cadrenal Therapeutics, Inc. (CVKD) CIK: 0001937993 Form: 8-K Filed at: 2025-08-05T23:59:59+00:00 Accession: 0001213900-25-071764 Event type: other_material Sentiment: positive Materiality: 0.65 Item codes: 8.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Cadrenal to begin tecarfarin trial in ESKD patients transitioning to dialysis later this year -------------------------------------------------------------------------------- - Trial includes ESKD patients with and without atrial fibrillation, enrollment planned to begin later this year. - Tecarfarin has orphan drug and fast-track designations for ESKD+AFib, highlighting unmet need. - Addresses critical gap: no proven anticoagulant for dialysis initiation period, which carries excess cardiovascular risk. - CEO Quang X. Pham calls the study an important step forward for tecarfarin development. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1937993/000121390025071764/0001213900-25-071764-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1937993/000121390025071764/ea0251809-8k_cadrenal.htm HTML page: https://secwatch.observer/filing/0001213900-25-071764 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer