other_material
confidence high
sentiment positive
materiality 0.70
Allarity Therapeutics: Phase 2 stenoparib shows median overall survival >25 months for platinum-resistant ovarian cancer
Allarity Therapeutics, Inc.
- Median overall survival (mOS) now exceeds 25 months, not yet formally reached, in ongoing Phase 2 trial.
- Two patients remain on therapy >24 months; one with BRCA wild-type shows benefit, typically precluded by PARP inhibitors.
- Data presented at AACR 2025 Ovarian Cancer Conference; FDA draft guidance supports OS as endpoint for approval.
- Stenoparib shows less myelotoxicity vs earlier PARP inhibitors, relevant after 2022 market withdrawal of some PARP inhibitors.
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