other material
confidence high
sentiment positive
materiality 0.70
Citius Pharmaceuticals reports positive Phase 1 topline results for LYMPHIR/pembrolizumab combo in gynecologic cancers
Citius Pharmaceuticals, Inc.
- Phase 1 trial of LYMPHIR plus KEYTRUDA in 25 evaluable patients with relapsed/refractory gynecologic cancers showed 24% objective response rate and 48% clinical benefit rate.
- No unexpected safety signals or serious immune-related adverse events were observed at any dose level in the University of Pittsburgh-led study.
- Full safety and efficacy results expected to be presented at an international cancer conference later this year.
- Study investigators highlight potential for LYMPHIR to augment immune checkpoint inhibitor efficacy in ovarian cancer.