---
schema_version: "secwatch.filing_event.v1"
accession: "0001213900-26-077134"
form_type: "8-K"
ticker: "CVKD"
cik: "0001937993"
company_name: "Cadrenal Therapeutics, Inc."
filed_at: "2026-07-10T20:05:16+00:00"
generated_at: "2026-07-10T20:06:18.243826+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.5
calibrated_materiality_score: 0.5
confidence: "high"
source: SEC EDGAR
---

# Cadrenal Therapeutics CMO James J. Ferguson III resigns effective July 31, 2026

## Summary
- James J. Ferguson III, Chief Medical Officer, resigned effective July 31, 2026.
- Company is conducting a search for Dr. Ferguson's replacement.
- Company and Dr. Ferguson are negotiating terms of a separation agreement and release.

## SEC filing metadata
- accession: 0001213900-26-077134
- form_type: 8-K
- ticker: CVKD
- cik: 0001937993
- company_name: Cadrenal Therapeutics, Inc.
- filed_at: 2026-07-10T20:05:16+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.5
- calibrated_materiality_score: 0.5
- confidence: high
- sec_items: 5.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1937993/000121390026077134/0001213900-26-077134-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1937993/000121390026077134/ea0297603-8k_cadrenal.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001213900-26-077134
- JSON: https://secwatch.observer/filing/0001213900-26-077134.json
- Plain text: https://secwatch.observer/filing/0001213900-26-077134.txt

## Key facts
- Executive change
  James J. Ferguson III resigned as Chief Medical Officer at Cadrenal Therapeutics, Inc..
  - Action: resigned
  - Role: Chief Medical Officer
  source text: On July 7, 2026, James J. Ferguson III, Chief Medical Officer of Cadrenal Therapeutics, Inc. (the “Company”), advised the Board of Directors of the Company of his decision to resign from his position as Chief Medical Officer of the Company, effective July 31, 2026 (the “Separation Date”).
  evidence_url: https://www.sec.gov/Archives/edgar/data/1937993/000121390026077134/0001213900-26-077134-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.