other material
confidence high
sentiment positive
materiality 0.60
Jasper Therapeutics completes IgAN enrollment for vensobafusp alfa Phase 2; adds FSGS cohort
Jasper Therapeutics, Inc.
- 18 IgAN patients enrolled in stage 1 across 3 cohorts: subcutaneous Q2W (n=6), Q4W (n=6) and Q8W (n=6) maintenance dosing.
- Initial interim IgAN data from the Phase 2 basket study expected by year-end 2026; stage 1 assesses safety, tolerability and initial efficacy.
- New FSGS cohort added to the basket study, with first patients anticipated to be dosed in the first quarter of 2027.
- Study runs in China with partner Kira; vensobafusp alfa (KP104) is a bifunctional biologic targeting both alternative and terminal complement pathways.
- CMO Greg Keenan said enrollment completed on schedule; company is exploring additional cohorts in other complement-mediated kidney diseases.