{"schema_version":"secwatch.filing_event.v1","accession":"0001214659-26-012132","form_type":"8-K","ticker":"ALZN","cik":"0001677077","company_name":"Alzamend Neuro, Inc.","filed_at":"2026-09-29T10:30:19+00:00","discovered_at":"2026-09-29T10:35:00.275491+00:00","generated_at":"2026-10-12T13:41:02.036211+00:00","sec_items":["7.01","9.01"],"event_type":"other_material","sentiment":"neutral","materiality_score":0.5,"calibrated_materiality_score":0.5,"confidence":"high","headline":"Alzamend Neuro presents Phase 1/2A AL001 lithium brain-imaging data at ISMRT on Sept. 29, 2026","bullets":["Dr. Ovidiu C. Andronesi presented Phase 1/2A results at the ISMRT Workshop on Sept. 29, 2026, covering 30 participants: 6 each healthy, bipolar, major depression, Alzheimer's, and PTSD.","AL001 is a lithium salicylate/L-proline co-crystal; trial NCT06921590 used 7T Terra.X MRI and compared AL001 with Li2CO3 in a randomized crossover.","Brain Li concentration trended higher after AL001 (geometric mean 4020.64 ng/g, 64% CV) vs Li2CO3 (3476.94 ng/g, 57% CV), but differences were not statistically significant.","Non-compartmental PK AUC trended higher for AL001 (geometric mean 62230 h*ng/g, 26% CV) vs Li2CO3 (59715 h*ng/g, 25% CV); two-compartment modeling showed higher white-matter K1.","92% of lithium images were scored excellent to adequate, with Gwet's agreement coefficient 0.73 (95% CI 0.66-0.80)."],"urls":{"canonical":"https://secwatch.observer/filing/0001214659-26-012132","json":"https://secwatch.observer/filing/0001214659-26-012132.json","markdown":"https://secwatch.observer/filing/0001214659-26-012132.md","text":"https://secwatch.observer/filing/0001214659-26-012132.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1677077/000121465926012132/0001214659-26-012132-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1677077/000121465926012132/x9282618k.htm"},"model":{"generated_by":"deepseek-v4.1-flash:cloud@v2","generated_at":"2026-10-12T13:41:02.036211+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}