---
schema_version: "secwatch.filing_event.v1"
accession: "0001321732-22-000016"
form_type: "8-K"
ticker: "PEN"
cik: "0001321732"
company_name: "Penumbra Inc"
filed_at: "2022-02-22T23:59:59+00:00"
generated_at: "2026-06-27T05:57:39.302358+00:00"
event_type: "earnings"
sentiment: "positive"
materiality_score: 0.65
calibrated_materiality_score: 0.65
confidence: "high"
source: SEC EDGAR
---

# Penumbra Q4 2021 revenue $204M (+22% YoY); GAAP op loss $40.1M, adjusted op income $2.5M

## Summary
- Q4 revenue $204.0M (+22.2% YoY; +23.0% constant currency); US $144.5M (+23.7%).
- Vascular revenue $113.6M (+30.4%); neuro revenue $90.4M (+13.3%).
- GAAP operating loss $40.1M; non-GAAP op income $2.5M excluding $25.8M Sixense accelerated vesting and $15.0M Thunderbolt R&D milestone.
- Full year 2021 revenue $747.6M (+33.4%); non-GAAP op income $40.1M vs prior year loss of $22.5M.

## SEC filing metadata
- accession: 0001321732-22-000016
- form_type: 8-K
- ticker: PEN
- cik: 0001321732
- company_name: Penumbra Inc
- filed_at: 2022-02-22T23:59:59+00:00
- event_type: earnings
- sentiment: positive
- materiality_score: 0.65
- calibrated_materiality_score: 0.65
- confidence: high
- sec_items: 2.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1321732/000132173222000016/0001321732-22-000016-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1321732/000132173222000016/pen-20220222.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001321732-22-000016
- JSON: https://secwatch.observer/filing/0001321732-22-000016.json
- Plain text: https://secwatch.observer/filing/0001321732-22-000016.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.