other material
confidence high
sentiment positive
materiality 0.80
Altimmune reports pemvidutide Phase 1b MASLD data: LFC reduced up to 68.5%
Altimmune, Inc.
- Pemvidutide reduced liver fat content (LFC) by up to 68.5% from baseline over 12 weeks in 94 MASLD patients.
- Total cholesterol decreased by up to 12.2% and triglycerides by up to 44.6% after 12 weeks of treatment.
- Presented at AASLD The Liver Meeting from a 12-week Phase 1b trial in overweight/obese MASLD subjects.
- Subjects received once-weekly subcutaneous pemvidutide (1.2mg, 1.8mg, 2.4mg) or placebo.