secwatch.observer — SEC 8-K summary ====================================== Issuer: SUPERNUS PHARMACEUTICALS, INC. (SUPN) CIK: 0001356576 Form: 8-K Filed at: 2024-10-30T23:59:59+00:00 Accession: 0001356576-24-000062 Event type: other_material Sentiment: positive Materiality: 0.80 Item codes: 7.01 LLM model: deepseek-v4-flash:cloud@v2 Supernus SPN-820 Phase 2a shows rapid antidepressant response: 50% MADRS rate at 4 hours -------------------------------------------------------------------------------- - SPN-820 achieved 50.0% MADRS response rate and 35.0% remission rate at 4 hours post-dose in open-label Phase 2a study. - By Day 10, response rate improved to 84.2% and remission to 63.2% in adults with major depressive disorder. - Company notes positive early data; continues development and discussions with potential partners for Sunseeker asset. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1356576/000135657624000062/0001356576-24-000062-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1356576/000135657624000062/supn-20241030.htm HTML page: https://secwatch.observer/filing/0001356576-24-000062 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer