other material
confidence high
sentiment positive
materiality 0.85
Kiora's KIO-301 shows vision improvement in blind RP patients in Phase I/II trial
KIORA PHARMACEUTICALS INC
- Visual field increased significantly (p<0.05) at days 7 and 14; high-dose group gained 0.30 logMAR (3 lines) visual acuity.
- Functional MRI showed increased brain activity in visual cortex; mobility test improvement from 24.7% to 60.0% at day 28.
- No serious adverse events or retinal inflammation; duration of effect supports monthly IVT injection.
- Company plans sham-controlled Phase II trial in 2024; will share ABACUS results with FDA in Q4 2023.
- Patients with no light perception regained ability to perceive light; Odds Ratio 2.1-4.2 for light perception improvement.