Pacira BioSciences cuts 71 jobs (8% of workforce); decommissions 45-liter EXPAREL suite in San Diego

Pacira BioSciences, Inc.

Workforce reduction of 71 employees (~8% of total) from Technical Operations at San Diego Science Center Campus.
Pre-tax charges of $2.4M-$2.8M in Q3 2025 for employee termination benefits, plus $5.4M accelerated depreciation.
Decommissioning 45-liter manufacturing suite after bringing two larger 200+ liter suites online in San Diego and Swindon, UK.
Expects annual operating expense savings of ~$13 million from the reduction in force.
New large-scale suites produce bulk EXPAREL volumes approximately four-fold greater per batch, improving gross margins.

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