{"schema_version":"secwatch.filing_event.v1","accession":"0001404644-25-000044","form_type":"8-K","ticker":"NGNE","cik":"0001404644","company_name":"Neurogene Inc.","filed_at":"2025-05-09T23:59:59+00:00","discovered_at":"2026-05-14T18:02:48.180640+00:00","generated_at":"2026-05-22T01:30:32.513137+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"positive","materiality_score":0.65,"calibrated_materiality_score":0.65,"confidence":"high","headline":"Neurogene reports Q1 net loss of $22.6M; cash $292.6M; NGN-401 trial on track","bullets":["Net loss of $22.6M for Q1 2025 vs $16.9M Q1 2024; R&D expenses rose to $17.8M from $13.5M.","Cash, equivalents and short-term investments of $292.6M as of March 31, 2025; runway into H2 2027.","NGN-401 gene therapy for Rett syndrome: registrational trial plan update expected in H1 2025; interim clinical data in H2 2025.","Enrolling additional participants in Phase 1/2 trial; pediatric cohort (age 4-10, N=8) and older cohort (11+, N=3).","Peer-reviewed publication in Science Translational Medicine validating EXACT transgene regulation technology."],"urls":{"canonical":"https://secwatch.observer/filing/0001404644-25-000044","json":"https://secwatch.observer/filing/0001404644-25-000044.json","markdown":"https://secwatch.observer/filing/0001404644-25-000044.md","text":"https://secwatch.observer/filing/0001404644-25-000044.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1404644/000140464425000044/0001404644-25-000044-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1404644/000140464425000044/ngne-20250509.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-22T01:30:32.513137+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}