other material
confidence high
sentiment positive
materiality 0.65
iBio reports single-dose IBIO-610 achieves 98% Activin E inhibition at 4 weeks in obese NHP study
iBio, Inc.
- Single dose of IBIO-610 reduced active Activin E by 98% at week 4 and 97% at week 8 vs baseline in obese NHPs.
- When combined with semaglutide, IBIO-610 reduced lean mass loss by 73% versus semaglutide alone.
- Data supports potential for infrequent dosing and fat-selective weight loss while preserving lean mass.
- Full dataset to be presented at EASD Annual Meeting in Milan, September 28 – October 2, 2026.