---
schema_version: "secwatch.filing_event.v1"
accession: "0001437402-25-000021"
form_type: "8-K"
ticker: "ARDX"
cik: "0001437402"
company_name: "ARDELYX, INC."
filed_at: "2025-12-17T23:59:59+00:00"
generated_at: "2026-05-16T12:54:28.023320+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.55
calibrated_materiality_score: 0.55
confidence: "high"
source: SEC EDGAR
---

# Ardelyx CLO and CMO resign effective Dec 31; interim CMO appointed

## Summary
- Elizabeth Grammer resigns as Chief Legal and Administrative Officer effective Dec 31, 2025; will serve as General Counsel then Senior Advisor for 24 months.
- Edward Conner resigns as CMO effective Dec 31, 2025 for personal reasons; Dr. Laura Williams appointed interim CMO.
- Grammer transition agreement: retains base salary, target bonus 45% for 2025, no ongoing bonus as advisor; equity continues vesting.
- Laura Williams, former CMO and current Chief Patient Officer, serves as interim CMO until permanent hire.

## SEC filing metadata
- accession: 0001437402-25-000021
- form_type: 8-K
- ticker: ARDX
- cik: 0001437402
- company_name: ARDELYX, INC.
- filed_at: 2025-12-17T23:59:59+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.55
- calibrated_materiality_score: 0.55
- confidence: high
- sec_items: 5.02, 8.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1437402/000143740225000021/0001437402-25-000021-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1437402/000143740225000021/ardx-20251217.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001437402-25-000021
- JSON: https://secwatch.observer/filing/0001437402-25-000021.json
- Plain text: https://secwatch.observer/filing/0001437402-25-000021.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.