other material
confidence high
sentiment neutral
materiality 0.70
Pieris doses first subject in Phase 1 trial of inhaled CTGF inhibitor PRS-220 for IPF
PALVELLA THERAPEUTICS, INC.
- First subject dosed in Phase 1 dose-escalation study of PRS-220, an inhaled Anticalin protein targeting CTGF.
- Study evaluating safety, tolerability, and PK in healthy volunteers; results expected in 2023.
- IPF affects over 3 million patients worldwide; median survival 3-5 years from diagnosis.
- PRS-220 is the second inhaled respiratory program Pieris has brought into the clinic.
- CEO Stephen Yoder highlights potential for meaningful improvement in quality of life for IPF patients.