---
schema_version: "secwatch.filing_event.v1"
accession: "0001437749-23-022782"
form_type: "8-K"
ticker: "DYAI"
cik: "0001213809"
company_name: "DYADIC INTERNATIONAL INC"
filed_at: "2023-08-09T23:59:59+00:00"
generated_at: "2026-06-11T21:31:34.816260+00:00"
event_type: "earnings"
sentiment: "positive"
materiality_score: 0.75
calibrated_materiality_score: 0.75
confidence: "high"
source: SEC EDGAR
---

# Dyadic Q2 net loss narrows to $2.15M; positive Phase 1 safety data for COVID booster DYAI-100

## Summary
- Net loss $2.15M (-$0.07/sh) vs -$3.29M (-$0.12/sh) YoY; revenue $837K up from $659K.
- Positive interim Phase 1 data: no major safety issues, immune response at both low and high doses of DYAI-100.
- Cash $10.2M at June 30, 2023, down from $12.7M at Dec 31, 2022.
- New fully funded collaborations: Top 5 pharma for vaccine antigen, EDCL in Bangladesh, Fermbox for alternative proteins.
- Developed animal-free recombinant serum albumin; structurally equivalent to animal-derived product.

## SEC filing metadata
- accession: 0001437749-23-022782
- form_type: 8-K
- ticker: DYAI
- cik: 0001213809
- company_name: DYADIC INTERNATIONAL INC
- filed_at: 2023-08-09T23:59:59+00:00
- event_type: earnings
- sentiment: positive
- materiality_score: 0.75
- calibrated_materiality_score: 0.75
- confidence: high
- sec_items: 2.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1213809/000143774923022782/0001437749-23-022782-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1213809/000143774923022782/dyai20230531_8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001437749-23-022782
- JSON: https://secwatch.observer/filing/0001437749-23-022782.json
- Plain text: https://secwatch.observer/filing/0001437749-23-022782.txt

## Key facts
- Earnings Releases
  DYADIC INTERNATIONAL INC reported financial results for the second quarter of 2023.
  - Period: the second quarter of 2023
  - Result: reported results
  source text: On August 9, 2023, Dyadic International, Inc. ("Dyadic") issued a press release announcing its results for the quarter ended June 30, 2023.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1213809/000143774923022782/0001437749-23-022782-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.