other material
confidence high
sentiment positive
materiality 0.50
Monopar reports positive preclinical imaging data for MNPR-101-Lu in pancreatic cancer model
Monopar Therapeutics
- SPECT imaging shows high specificity and durable uptake of MNPR-101-Lu in tumor relative to normal tissue in human pancreatic cancer xenograft model.
- Data help explain near complete tumor elimination observed after single injection of therapeutic radioisotopes bound to MNPR-101 in prior studies.
- MNPR-101-Lu uses Lutetium-177, same therapeutic radioisotope as commercially successful Pluvicto and Lutathera.
- Phase 1 dosimetry trial for diagnostic counterpart MNPR-101-Zr recently cleared by HREC in Australia for advanced cancer patients.