other material
confidence high
sentiment neutral
materiality 0.60
Monopar initiates Phase 1 dosimetry trial for MNPR-101-Zr in advanced cancers
Monopar Therapeutics
- Trial open for enrollment at Melbourne Theranostic Innovation Centre; led by Prof. Rodney Hicks.
- Evaluating safety/dosimetry in up to 12 advanced cancer patients using total-body PET/CT scanner.
- MNPR-101 targets uPAR expressed on pancreatic, breast, colorectal, and bladder tumors.
- Preclinical data show specific tumor uptake; if Phase 1 positive, plan to test MNPR-101 with therapeutic Ac-225.