other material
confidence high
sentiment negative
materiality 0.75
Pieris Pharmaceuticals' Servier collaboration terminated; S095012 Phase 1 halted on safety concern
PALVELLA THERAPEUTICS, INC.
- Servier terminated license/collaboration agreement effective Dec 27, 2024, citing a potential safety concern in the S095012 Phase 1 study.
- Pieris will discontinue all development of S095012; no further pursuit of the asset.
- Non-exclusive Anticalin platform license also terminates with the collaboration agreement.
- Pieris remains eligible for milestones from Boston Pharma and Pfizer partnerships on other 4-1BB bispecific assets: up to $200M development and >$415M commercial milestones.