other material
confidence high
sentiment neutral
materiality 0.65
CervoMed presents Phase 2a biomarker data at AAIC; neflamapimod reduces plasma GFAP in early DLB
CervoMed Inc.
- Poster at AAIC 2024: baseline plasma GFAP highly correlated with CDR-SB dementia severity in DLB patients.
- In early-stage DLB (no AD co-pathology), neflamapimod reduced plasma GFAP by mean 10.6 pg/mL vs placebo increase of 14.1 pg/mL (p=0.04).
- Reduction in GFAP correlated with improvement in CDR-SB in neflamapimod-treated early DLB patients (r=0.54, p=0.04).
- Fully enrolled RewinD-LB Phase 2b trial to report topline primary efficacy results in December 2024.
- Management to participate in fireside chat at Canaccord Genuity 44th Annual Growth Conference on August 13, 2024.