---
schema_version: "secwatch.filing_event.v1"
accession: "0001437749-24-029206"
form_type: "8-K"
ticker: "PBYI"
cik: "0001401667"
company_name: "PUMA BIOTECHNOLOGY, INC."
filed_at: "2024-09-16T23:59:59+00:00"
generated_at: "2026-05-31T04:32:58.948821+00:00"
event_type: "litigation"
sentiment: "negative"
materiality_score: 0.75
calibrated_materiality_score: 0.75
confidence: "high"
source: SEC EDGAR
---

# Puma reports judge invalidated Tagrisso patents; Wyeth appeals Sept 12

## Summary
- Jury awarded $107.5M for past infringement of '314 and '162 patents through Dec 2023.
- Judge granted AstraZeneca's motion, ruling patents invalid for lack of enablement/written description.
- Wyeth filed notice of appeal on Sept 12, 2024, challenging the invalidity ruling and other adverse orders.
- Puma was dismissed as plaintiff but retains contractual rights to recover damages under Pfizer agreement.
- Puma respectfully disagrees with the invalidity ruling; post-trial motions for supplemental damages and ongoing royalties pending.

## SEC filing metadata
- accession: 0001437749-24-029206
- form_type: 8-K
- ticker: PBYI
- cik: 0001401667
- company_name: PUMA BIOTECHNOLOGY, INC.
- filed_at: 2024-09-16T23:59:59+00:00
- event_type: litigation
- sentiment: negative
- materiality_score: 0.75
- calibrated_materiality_score: 0.75
- confidence: high
- sec_items: 8.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1401667/000143774924029206/0001437749-24-029206-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1401667/000143774924029206/pbyi20240913_8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001437749-24-029206
- JSON: https://secwatch.observer/filing/0001437749-24-029206.json
- Plain text: https://secwatch.observer/filing/0001437749-24-029206.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.