other material
confidence high
sentiment positive
materiality 0.55
Genprex partners with U Michigan to study REQORSA plus ALK-inhibitors in ALK+ lung cancer
Genprex, Inc.
- Entered Sponsored Research Agreement with Univ. of Michigan Rogel Cancer Center for TUSC2/REQORSA combo with ALK-inhibitors.
- Collaboration with ALK Positive nonprofit; both share cost of the SRA.
- Preclinical data (AACR Apr 2024): REQORSA induced apoptosis in alectinib-resistant EML4-ALK+ NSCLC lines.
- TUSC2 overexpression via REQORSA decreased cell growth and proliferation through apoptotic pathway activation.