other material
confidence high
sentiment positive
materiality 0.75
CervoMed reports Phase 2a biomarker data for neflamapimod in DLB; RewinD-LB topline due Dec 2024
CervoMed Inc.
- Plasma GFAP significantly reduced by neflamapimod (p=0.015 vs placebo); reductions linked to clinical improvement.
- RewinD-LB Phase 2b trial fully enrolled; topline data expected December 2024.
- Study has >95% statistical power for primary endpoint (CDR-SB) after excluding patients with tau pathology.
- DLB affects >1.4M patients in U.S. and EU with no approved treatment, per CervoMed.