other material
confidence high
sentiment positive
materiality 0.65
Monopar doses first patient with uPAR-targeted radiopharmaceutical MNPR-101-Lu
Monopar Therapeutics
- First patient dosed under US compassionate use protocol for metastatic pancreatic cancer.
- MNPR-101-Lu targets uPAR; infusion well-tolerated with no serious adverse reactions.
- Patient's tumor showed uPAR expression via prior MNPR-101-Zr PET/CT imaging.
- Two Phase 1 studies ongoing in Australia for MNPR-101-Zr (imaging) and MNPR-101-Lu (treatment).
- Company believes this is the world's first dosing of a uPAR-targeted therapeutic radiopharmaceutical.