other material
confidence high
sentiment positive
materiality 0.65
DSMB recommends Vaxart's COVID-19 Phase 2b trial proceed; norovirus Phase 1 in H1 2025
Vaxart, Inc.
- DSMB recommends Phase 2b proceed after review of 30-day safety data from 400-participant sentinel cohort.
- Trial to enroll ~10,000 participants pending FDA review and BARDA approval.
- Norovirus Phase 1 trial of second-gen vs first-gen constructs to start H1 2025, topline data mid-2025.
- New avian influenza vaccine candidate (clade 2.3.4.4b) in preclinical studies.
- Cash runway into 2026 supported by BARDA award of up to $460.7M.