---
schema_version: "secwatch.filing_event.v1"
accession: "0001437749-25-002265"
form_type: "8-K"
ticker: "CLNN"
cik: "0001822791"
company_name: "Clene Inc."
filed_at: "2025-01-30T23:59:59+00:00"
generated_at: "2026-05-27T05:43:43.909418+00:00"
event_type: "other_material"
sentiment: "positive"
materiality_score: 0.6
calibrated_materiality_score: 0.6
confidence: "high"
source: SEC EDGAR
---

# Clene enters subaward amendment for up to $8M from NIH for ALS Expanded Access Program

## Summary
- Amendment with Columbia University on Jan 28, 2025, extends funding for Year 2 of ACT-EAP from Sep 1, 2024 to Aug 31, 2025.
- Additional $7,976,230 obligated; cumulative funding to date totals $15,324,600.
- Supports CNM-Au8 treatment in ALS under the Accelerating Access to Critical Therapies for ALS Act.
- Other Subaward terms from April 2024 remain unchanged.

## SEC filing metadata
- accession: 0001437749-25-002265
- form_type: 8-K
- ticker: CLNN
- cik: 0001822791
- company_name: Clene Inc.
- filed_at: 2025-01-30T23:59:59+00:00
- event_type: other_material
- sentiment: positive
- materiality_score: 0.6
- calibrated_materiality_score: 0.6
- confidence: high
- sec_items: 1.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1822791/000143774925002265/0001437749-25-002265-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1822791/000143774925002265/clnn20241218_8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001437749-25-002265
- JSON: https://secwatch.observer/filing/0001437749-25-002265.json
- Plain text: https://secwatch.observer/filing/0001437749-25-002265.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.