---
schema_version: "secwatch.filing_event.v1"
accession: "0001437749-25-008869"
form_type: "8-K"
ticker: "CLNN"
cik: "0001822791"
company_name: "Clene Inc."
filed_at: "2025-03-24T23:59:59+00:00"
generated_at: "2026-05-24T06:51:12.854942+00:00"
event_type: "earnings"
sentiment: "neutral"
materiality_score: 0.7
calibrated_materiality_score: 0.7
confidence: "high"
source: SEC EDGAR
---

# Clene reports FY2024 net loss $39.4M ($5.67/sh); plans NDA for CNM-Au8 in ALS in H2 2025

## Summary
- Net loss $39.4M ($5.67/sh) vs. $49.5M ($9.43/sh) in FY2023.
- Cash and marketable securities $12.2M at Dec 31, 2024; expected to fund ops into Q2 2025.
- R&D expense $20.1M, down 25% YoY; G&A $13.3M, down 8%.
- Planning NDA submission for CNM-Au8 in ALS in H2 2025; confirmatory Phase 3 RESTORE-ALS starts mid-2025.
- Secured new $10M debt facility (12% interest, convertible at $5.67) replacing $7.85M Avenue debt.

## SEC filing metadata
- accession: 0001437749-25-008869
- form_type: 8-K
- ticker: CLNN
- cik: 0001822791
- company_name: Clene Inc.
- filed_at: 2025-03-24T23:59:59+00:00
- event_type: earnings
- sentiment: neutral
- materiality_score: 0.7
- calibrated_materiality_score: 0.7
- confidence: high
- sec_items: 2.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1822791/000143774925008869/0001437749-25-008869-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1822791/000143774925008869/clnn20240924_8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001437749-25-008869
- JSON: https://secwatch.observer/filing/0001437749-25-008869.json
- Plain text: https://secwatch.observer/filing/0001437749-25-008869.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.