{"schema_version":"secwatch.filing_event.v1","accession":"0001437749-25-013235","form_type":"8-K","ticker":"GNPX","cik":"0001595248","company_name":"Genprex, Inc.","filed_at":"2025-04-28T23:59:59+00:00","discovered_at":"2026-05-14T18:02:48.939888+00:00","generated_at":"2026-05-23T04:58:47.211473+00:00","sec_items":["8.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.6,"calibrated_materiality_score":0.6,"confidence":"high","headline":"Genprex licenses NYU patent for Reqorsa gene therapy in mesothelioma; TUSC2 down in 84%","bullets":["Exclusive patent license with NYU Langone Health for Reqorsa (quaratusugene ozeplasmid) to treat mesothelioma.","TUSC2 tumor suppressor gene is downregulated in 84% of mesotheliomas; Reqorsa delivers TUSC2.","Preclinical data showed decreased cell proliferation/invasion and increased apoptosis in all four MPM cell lines.","Genprex formed a Mesothelioma Clinical Advisory Board of four leading researchers to guide the program.","About 3,000 new US cases/yr; life expectancy 18 months, 3-year survival rate 23% with treatment."],"urls":{"canonical":"https://secwatch.observer/filing/0001437749-25-013235","json":"https://secwatch.observer/filing/0001437749-25-013235.json","markdown":"https://secwatch.observer/filing/0001437749-25-013235.md","text":"https://secwatch.observer/filing/0001437749-25-013235.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1595248/000143774925013235/0001437749-25-013235-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1595248/000143774925013235/gnpx20250424_8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-23T04:58:47.211473+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}