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Genprex enters new sponsored research agreement with University of Pittsburgh for GPX-002 diabetes gene therapy
Genprex, Inc.
- New SRA with Pitt for preclinical studies of GPX-002 in T1D and T2D animal models.
- Preclinical T1D data showed statistically significant decreases in insulin requirements and increases in c-peptide levels.
- GPX-002 uses adeno-associated virus vector with Pdx1 and MafA genes delivered via pancreatic duct.
- In T1D, GPX-002 aims to transform alpha cells into functional beta-like cells to evade immune system.
- In T2D, GPX-002 is believed to rejuvenate exhausted beta cells.