other_material
confidence high
sentiment positive
materiality 0.65
Phio completes enrollment in Phase 1b trial of PH-762; positive pathologic responses
Phio Pharmaceuticals Corp.
- 18 patients treated across 5 dose cohorts; 16 with cSCC, 1 Merkel cell, 1 melanoma.
- cSCC responses: 6 complete (100% clearance), 2 near complete (>90%), 2 partial (>50%).
- Merkel cell patient had partial response (>50% clearance); no patients showed disease progression.
- No dose-limiting toxicities or clinically relevant treatment-emergent adverse effects reported.
- Highest dose cohort still enrolling; pathology results expected Q1 2026.
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