---
schema_version: "secwatch.filing_event.v1"
accession: "0001437749-25-036713"
form_type: "8-K"
ticker: "CLNN"
cik: "0001822791"
company_name: "Clene Inc."
filed_at: "2025-12-03T23:59:59+00:00"
generated_at: "2026-05-16T15:24:19.048853+00:00"
event_type: "other_material"
sentiment: "neutral"
materiality_score: 0.3
calibrated_materiality_score: 0.3
confidence: "low"
source: SEC EDGAR
---

# Clene hosts ALS program update call; no specific data disclosed in filing

## Summary
- Company held conference call on December 3, 2025, regarding CNM-Au8 ALS program.
- Presentation furnished as Exhibit 99.1 but not textually included in filing.
- No financial results, clinical data, or regulatory milestones reported in the 8-K.
- Event type is Regulation FD disclosure; no new materially quantifiable information.

## SEC filing metadata
- accession: 0001437749-25-036713
- form_type: 8-K
- ticker: CLNN
- cik: 0001822791
- company_name: Clene Inc.
- filed_at: 2025-12-03T23:59:59+00:00
- event_type: other_material
- sentiment: neutral
- materiality_score: 0.3
- calibrated_materiality_score: 0.3
- confidence: low
- sec_items: 7.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1822791/000143774925036713/0001437749-25-036713-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1822791/000143774925036713/clnn20251201_8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001437749-25-036713
- JSON: https://secwatch.observer/filing/0001437749-25-036713.json
- Plain text: https://secwatch.observer/filing/0001437749-25-036713.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.