secwatch.observer — SEC 8-K summary ====================================== Issuer: Contineum Therapeutics, Inc. (CTNM) CIK: 0001855175 Form: 8-K Filed at: 2025-12-11T23:59:59+00:00 Accession: 0001437749-25-037547 Event type: other_material Sentiment: neutral Materiality: 0.60 Item codes: 8.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Contineum Therapeutics starts Phase 2 trial of PIPE-791 for IPF; 324 subjects, completion June 2028 -------------------------------------------------------------------------------- - Submitted Phase 2 trial details for PIPE-791 to ClinicalTrials.gov; expects ~324 IPF patients enrolled globally. - Trial is 26-week, randomized, dose-ranging, double-blind, placebo-controlled, once-daily dosing. - Primary efficacy endpoint: change from baseline in forced vital capacity (FVC) at week 26. - Trial design informed by regulatory feedback and completed Phase 1 data; completion expected June 2028. - No financial guidance or capital structure changes included in this filing. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1855175/000143774925037547/0001437749-25-037547-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1855175/000143774925037547/ctnm20251204_8k.htm HTML page: https://secwatch.observer/filing/0001437749-25-037547 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer