other material
confidence high
sentiment positive
materiality 0.75
Moleculin reports positive Phase 1 results for WP1066 in pediatric malignant brain tumors
Moleculin Biotech, Inc.
- WP1066 showed no significant toxicity and determined maximum feasible dose in 10 children with high-grade glioma.
- Partial tumor response observed in a DIPG patient; anti-tumor immune responses demonstrated via STAT3 suppression.
- Results published in Journal of Clinical Investigation Insight; Phase 2 trial warranted based on findings.
- Compassionate use in 3 additional children with high-grade glioma also evaluated.
- Study funded by Peach Bowl LegACy Fund and CURE Childhood Cancer.