{"schema_version":"secwatch.filing_event.v1","accession":"0001437749-26-000694","form_type":"8-K","ticker":"GNPX","cik":"0001595248","company_name":"Genprex, Inc.","filed_at":"2026-01-07T23:59:59+00:00","discovered_at":"2026-05-14T18:02:35.582812+00:00","generated_at":"2026-05-16T11:21:45.146254+00:00","sec_items":["7.01","8.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.6,"calibrated_materiality_score":0.6,"confidence":"medium","headline":"Genprex advances diabetes gene therapy GPX-002 into T2D preclinical studies, plans FDA meeting Q1 2026","bullets":["Initiated preclinical research in Type 2 diabetic animal models; in vivo proof-of-concept showed normalized glucose levels.","Submitted meeting request to FDA for Q1 2026 to discuss IND-enabling studies for GPX-002.","Transferred GPX-002 manufacturing to experienced CDMO; plans clinical-scale cGMP production.","Continuing construct optimization for second-generation GPX-002 using non-viral lipid nanoparticle delivery.","Toxicology studies to follow FDA interaction; data expected to enable IND filing."],"urls":{"canonical":"https://secwatch.observer/filing/0001437749-26-000694","json":"https://secwatch.observer/filing/0001437749-26-000694.json","markdown":"https://secwatch.observer/filing/0001437749-26-000694.md","text":"https://secwatch.observer/filing/0001437749-26-000694.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1595248/000143774926000694/0001437749-26-000694-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1595248/000143774926000694/gnpx20260105_8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-16T11:21:45.146254+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}