{"schema_version":"secwatch.filing_event.v1","accession":"0001437749-26-004455","form_type":"8-K","ticker":"MBRX","cik":"0001659617","company_name":"Moleculin Biotech, Inc.","filed_at":"2026-02-18T23:59:59+00:00","discovered_at":"2026-05-14T18:02:35.793075+00:00","generated_at":"2026-05-16T02:06:36.774067+00:00","sec_items":["7.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.85,"calibrated_materiality_score":0.85,"confidence":"high","headline":"Moleculin reports 40% blinded CRc in MIRACLE trial; 35 subjects treated, unblinding on track for Q1 2026","bullets":["Preliminary blinded composite CR rate of 40% (30% CR, 10% CRh) in first 30 subjects; 67% above historical cytarabine CR.","35 subjects treated to date with 11 in screening; targeting first unblinding at 45 subjects, on track for Q1 2026 treatment milestone.","Roughly 35% of treated subjects are venetoclax regimen failures, a challenging population with high unmet need.","Continued absence of cardiotoxicity cited; Annamycin holds FDA Fast Track and Orphan Drug Designation for R/R AML."],"urls":{"canonical":"https://secwatch.observer/filing/0001437749-26-004455","json":"https://secwatch.observer/filing/0001437749-26-004455.json","markdown":"https://secwatch.observer/filing/0001437749-26-004455.md","text":"https://secwatch.observer/filing/0001437749-26-004455.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1659617/000143774926004455/0001437749-26-004455-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1659617/000143774926004455/mbrx20260216c_8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-16T02:06:36.774067+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}