secwatch.observer — SEC 8-K summary ====================================== Issuer: Genprex, Inc. (GNPX) CIK: 0001595248 Form: 8-K Filed at: 2026-02-23T23:59:59+00:00 Accession: 0001437749-26-004954 Event type: other_material Sentiment: positive Materiality: 0.65 Item codes: 8.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Genprex wins Japanese and European patent grants for REQORSA combos; Acclaim-3 update -------------------------------------------------------------------------------- - Japanese Patent Office issued favorable Appeal Decision to grant patent for REQORSA + PD-L1 antibodies. - European Patent Office granted patent for REQORSA + PD-1 antibodies to treat cancer. - Acclaim-3 Phase 2 expansion: enrollment of first 25 patients for interim analysis expected by H1 2026; interim analysis in H2 2026. - Phase 2 primary endpoint: 18-week progression-free survival rate; trial targets ~50 patients with ES-SCLC. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1595248/000143774926004954/0001437749-26-004954-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1595248/000143774926004954/gnpx20260220_8k.htm HTML page: https://secwatch.observer/filing/0001437749-26-004954 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer