other material
confidence high
sentiment positive
materiality 0.75
Moleculin reports Annamycin shows no clinically significant cardiotoxicity in 90-patient pooled analysis
Moleculin Biotech, Inc.
- Pooled analysis of 90 R/R AML patients across 5 trials; 78 had source-verified pre/post ejection fraction assessments.
- No patients met criteria for clinically significant left ventricular dysfunction; mean ejection fraction stable.
- Cardiac safety review conducted by Cleveland Clinic cardio-oncology laboratory.
- Data presented at EHA 2026 Congress; Annamycin dosed beyond conventional anthracycline lifetime limits.
- Management believes results support broader positioning in AML and other oncology indications.