{"schema_version":"secwatch.filing_event.v1","accession":"0001437749-26-016260","form_type":"8-K","ticker":"MBRX","cik":"0001659617","company_name":"Moleculin Biotech, Inc.","filed_at":"2026-05-12T13:30:19+00:00","discovered_at":"2026-05-12T13:31:00.254719+00:00","generated_at":"2026-05-12T13:31:21.712384+00:00","sec_items":["7.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.75,"calibrated_materiality_score":0.75,"confidence":"high","headline":"Moleculin reports Annamycin shows no clinically significant cardiotoxicity in 90-patient pooled analysis","bullets":["Pooled analysis of 90 R/R AML patients across 5 trials; 78 had source-verified pre/post ejection fraction assessments.","No patients met criteria for clinically significant left ventricular dysfunction; mean ejection fraction stable.","Cardiac safety review conducted by Cleveland Clinic cardio-oncology laboratory.","Data presented at EHA 2026 Congress; Annamycin dosed beyond conventional anthracycline lifetime limits.","Management believes results support broader positioning in AML and other oncology indications."],"urls":{"canonical":"https://secwatch.observer/filing/0001437749-26-016260","json":"https://secwatch.observer/filing/0001437749-26-016260.json","markdown":"https://secwatch.observer/filing/0001437749-26-016260.md","text":"https://secwatch.observer/filing/0001437749-26-016260.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1659617/000143774926016260/0001437749-26-016260-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1659617/000143774926016260/mbrx20260511d_8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-12T13:31:21.712384+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}