Moleculin reports preliminary blinded CR rate ~30% in MIRACLE trial; first unblinding before June 30

Moleculin Biotech, Inc.

• Preliminary blinded CRc >40%, CR ~30% vs. historical ~17-18% for cytarabine alone.
• First unblinding of 45-subject data expected before June 30, 2026; ~30 Annamycin + cytarabine vs 15 control.
• 56 of 90 subjects recruited in Part A as of May 1, 2026; on track for Q3 2026 completion.
• Over 30% of subjects are R/R to prior venetoclax regimen, a challenging population.
• Annamycin has FDA Fast Track and Orphan Drug Designations for R/R AML.

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