Genprex reports positive predictive biomarker data for Reqorsa in NSCLC at ASCO 2026

Genprex, Inc.

In NSCLC patients, Trop-2 H-score >100 and PTEN H-score <100 correlated with prolonged PFS (p=0.05, p=0.03).
Data from 18 patients across Acclaim-1 (osimertinib), Acclaim-2 (pembrolizumab), and Acclaim-3 (atezolizumab) trials.
High (3+) Trop-2 expression showed near-significant correlation with PFS (p=0.053); will be further investigated as biomarker.
In SCLC patients, Trop-2 levels were universally low; no significant correlation with PFS observed.

item 8.01 item 9.01

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