8-K
filed May 29, 2026, 9:26 AM ET
ticker MBRX
CIK 0001659617
other material
confidence high
sentiment positive
materiality 0.75
Moleculin ASCO data: Annamycin shows no cardiotoxicity at high cumulative doses
Moleculin Biotech, Inc.
- Pooled analysis of 90 patients: no significant LVEF change (mean diff -0.12%, p=0.84) across doses up to 2,970 mg/m².
- Independent Cleveland Clinic review confirms no drug-induced cardiotoxicity across ECGs, biomarkers, and adverse events.
- Phase 1b/2 AML study achieved 50% CR, 60% CRc, median overall survival 12.39 months; 50% of responders received transplant.
- Pivotal Phase 2b/3 MIRACLE trial unblinding of first 45 patients on track for June 2026.
Machine-readable event card
- schema_version
- secwatch.filing_event.v1
- accession
- 0001437749-26-018819
- form_type
- 8-K
- ticker
- MBRX
- cik
- 0001659617
- company_name
- Moleculin Biotech, Inc.
- filed_at
- 2026-05-29T13:26:14+00:00
- discovered_at
- 2026-05-29T13:27:00.310459+00:00
- generated_at
- 2026-05-29T13:27:23.070826+00:00
- sec_items
- ["7.01", "9.01"]
- event_type
- other_material
- sentiment
- positive
- materiality_score
- 0.75
- calibrated_materiality_score
- 0.75
- confidence
- high
- secwatch_canonical_url
- https://secwatch.observer/filing/0001437749-26-018819
- json_url
- https://secwatch.observer/filing/0001437749-26-018819.json
- markdown_url
- https://secwatch.observer/filing/0001437749-26-018819.md
- text_url
- https://secwatch.observer/filing/0001437749-26-018819.txt
- edgar_index_url
- https://www.sec.gov/Archives/edgar/data/1659617/000143774926018819/0001437749-26-018819-index.htm
- edgar_primary_document_url
- https://www.sec.gov/Archives/edgar/data/1659617/000143774926018819/mbrx20260529_8k.htm
- generated_by_model
- deepseek-v4-flash:cloud@v2
- review_status
- machine_generated
- human_reviewed
- false
- corrected
- false
- correction_note
- null
- correction_timestamp
- null
- superseded_by
- null
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