other material
confidence high
sentiment positive
materiality 0.75
Moleculin ASCO data: Annamycin shows no cardiotoxicity at high cumulative doses
Moleculin Biotech, Inc.
- Pooled analysis of 90 patients: no significant LVEF change (mean diff -0.12%, p=0.84) across doses up to 2,970 mg/m².
- Independent Cleveland Clinic review confirms no drug-induced cardiotoxicity across ECGs, biomarkers, and adverse events.
- Phase 1b/2 AML study achieved 50% CR, 60% CRc, median overall survival 12.39 months; 50% of responders received transplant.
- Pivotal Phase 2b/3 MIRACLE trial unblinding of first 45 patients on track for June 2026.