---
schema_version: "secwatch.filing_event.v1"
accession: "0001490978-26-000009"
form_type: "8-K"
ticker: "SDGR"
cik: "0001490978"
company_name: "Schrodinger, Inc."
filed_at: "2026-02-25T23:59:59+00:00"
generated_at: "2026-05-16T00:15:12.846069+00:00"
event_type: "earnings"
sentiment: "neutral"
materiality_score: 0.75
calibrated_materiality_score: 0.75
confidence: "high"
source: SEC EDGAR
---

# Schrödinger reports 2025 revenue $255.9M (+23%), net loss $103.3M; guides 2026 software ACV $218-228M

## Summary
- Software revenue $199.5M (+10.6%); drug discovery revenue $56.4M (+107%) vs $27.2M in 2024.
- Software ACV $198.5M, up 4% YoY; net loss $103.3M vs $187.1M; adjusted EBITDA -$114.9M vs -$152.5M.
- Accelerating transition to hosted software; GAAP software revenue expected to decline short-to-medium term while ACV unchanged.
- 2026 guidance: software ACV $218-228M (10-15% growth), drug discovery rev $55-65M, opex below 2025.
- 2028 objective: positive adjusted EBITDA by year-end, substantially complete hosted transition, drug discovery rev ~$50M/year.

## SEC filing metadata
- accession: 0001490978-26-000009
- form_type: 8-K
- ticker: SDGR
- cik: 0001490978
- company_name: Schrodinger, Inc.
- filed_at: 2026-02-25T23:59:59+00:00
- event_type: earnings
- sentiment: neutral
- materiality_score: 0.75
- calibrated_materiality_score: 0.75
- confidence: high
- sec_items: 2.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1490978/000149097826000009/0001490978-26-000009-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1490978/000149097826000009/sdgr-20260225.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001490978-26-000009
- JSON: https://secwatch.observer/filing/0001490978-26-000009.json
- Plain text: https://secwatch.observer/filing/0001490978-26-000009.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.