secwatch.observer — SEC 8-K summary ====================================== Issuer: Lineage Cell Therapeutics, Inc. (LCTX) CIK: 0000876343 Form: 8-K Filed at: 2022-03-10T23:59:59+00:00 Accession: 0001493152-22-006506 Event type: earnings Sentiment: neutral Materiality: 0.60 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Lineage Cell reports Q4 net loss $0.17/sh; cash $55.7M; Roche deal up to $670M ------------------------------------------------------------------------------ - Q4 2021 net loss $29.0M ($0.17/sh) vs net income $2.0M ($0.01/sh) in Q4 2020; FY 2021 net loss $43.0M ($0.26/sh). - Cash and equivalents $55.7M at Dec 31, 2021; received $50M upfront from Roche/Genentech OpRegen collaboration in Jan 2022. - Roche/Genentech deal for OpRegen (RG6501) worth up to $670M plus double-digit royalties; four dry AMD patients showed retinal restoration. - R&D expenses $24.8M in Q4, driven by $21.0M accrual for future obligations to Israel Innovation Authority and Hadasit. - 2022 milestones include new pipeline program announcement, OPC1 manufacturing improvements, and VAC2 IND submission in 2H 2022. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/876343/000149315222006506/0001493152-22-006506-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/876343/000149315222006506/form8-k.htm HTML page: https://secwatch.observer/filing/0001493152-22-006506 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer