secwatch.observer — SEC 8-K summary ====================================== Issuer: Oncotelic Therapeutics, Inc. (OTLC) CIK: 0000908259 Form: 8-K Filed at: 2022-07-15T23:59:59+00:00 Accession: 0001493152-22-019381 Event type: other_material Sentiment: positive Materiality: 0.70 Item codes: 7.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Oncotelic presents Phase 1/2 OT-101 pancreatic cancer data; median OS doubled in patients receiving subsequent chemo -------------------------------------------------------------------------------- - 55% of OT-101-treated pancreatic cancer patients had long-term disease control (21 of 37 pts). - Median OS doubled to 9.3 vs 2.6 months (p<0.0001) for those who received subsequent chemotherapy. - High AUC associated with improved OS: 9.6 vs 2.4 months (p=0.0006). - OT-101 PK dose proportional (p<0.0001). - Presentation from JCA-AACR conference available on company website and YouTube. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/908259/000149315222019381/0001493152-22-019381-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/908259/000149315222019381/form8-k.htm HTML page: https://secwatch.observer/filing/0001493152-22-019381 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer