other material
confidence high
sentiment positive
materiality 0.75
Anebulo reports positive interim Phase 2 data for ANEB-001 in acute cannabinoid intoxication
Anebulo Pharmaceuticals, Inc.
- Part B: 21mg THC challenge; 10mg or 30mg ANEB-001 significantly reduced VAS feeling high (p<0.001), improved alertness (p<0.01), and reduced body sway (p<0.01) vs placebo.
- Placebo group: 100% of subjects met VAS threshold for feeling high; only 1 subject per active dose group met threshold.
- Safety: adverse events mild/transient except two moderate dizziness cases in Cohort 1 likely THC-attributable.
- Company continuing Part B, enrolling third cohort; collaborating with FDA MIDD group on PK/PD model to optimize dosing for ACI.