other material
confidence high
sentiment positive
materiality 0.75
Bioxytran Phase 2 trial of ProLectin-M shows 100% viral clearance at day 7 in COVID-19 patients
BIOXYTRAN, INC
- 100% of treated patients achieved viral clearance by day 7 vs 6% placebo (p=.001); 88% by day 3 vs 0% placebo.
- No drug-related serious adverse events or viral rebounds during 14-day observation period.
- NMR data show ProLectin-M binds galectin-3 with micromolar affinity (2 μM) and blocks S1 subunit and ACE2 receptors.
- Results provide rationale for upcoming Phase 2/3 registrational trial.
- Company plans to explore the galectin antagonist platform for other viruses and indications.