secwatch.observer — SEC 8-K summary ====================================== Issuer: Shuttle Pharmaceuticals Holdings, Inc. (SHPH) CIK: 0001757499 Form: 8-K Filed at: 2023-03-22T23:59:59+00:00 Accession: 0001493152-23-008489 Event type: other_material Sentiment: positive Materiality: 0.70 Item codes: 1.01, 4.01, 7.01, 8.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Shuttle Pharma enters research agreement with Georgetown for HDAC6 inhibitor SP-2-225 -------------------------------------------------------------------------------- - Research agreement with Georgetown University for up to $128,400 to test SP-2-225 in breast cancer model. - Agreement runs April 1, 2023 to March 31, 2024; supports IND-enabling studies in 2023. - Plans to submit IND and start Phase I clinical trial for SP-2-225 in 2024. - Auditor changed from BF Borgers CPA PC to FORVIS LLP effective March 21, 2023; no disagreements. - Going concern opinion from 2021 resolved after $11.4M IPO and $4.0M private placement. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1757499/000149315223008489/0001493152-23-008489-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1757499/000149315223008489/form8-k.htm HTML page: https://secwatch.observer/filing/0001493152-23-008489 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer