other material
confidence high
sentiment neutral
materiality 0.75
Matinas BioPharma concludes BioNTech mRNA collaboration, plans Phase 3 trial for MAT2203 antifungal
Matinas BioPharma Holdings, Inc.
- BioNTech oral mRNA collaboration ended; in vivo oral study showed no activity, but systemic delivery and stability demonstrated.
- Company plans to submit revised Phase 3 trial design for MAT2203 in aspergillosis and other IFIs in Q2 2023.
- Seven patients with IFIs treated under compassionate use; oral MAT2203 showed safety and efficacy in diverse infections.
- Cash position sufficient to fund operations into second half of 2024.
- Expanded collaboration with National Resilience for mRNA/oligonucleotide delivery; initial data expected Q3 2023.