---
schema_version: "secwatch.filing_event.v1"
accession: "0001493152-23-032175"
form_type: "8-K"
ticker: "CING"
cik: "0001862150"
company_name: "Cingulate Inc."
filed_at: "2023-09-11T23:59:59+00:00"
generated_at: "2026-06-10T21:51:02.770628+00:00"
event_type: "other_material"
sentiment: "neutral"
materiality_score: 0.75
calibrated_materiality_score: 0.75
confidence: "high"
source: SEC EDGAR
---

# Cingulate reports Phase 3 CTx-1301 trend toward significance; insider debt conversion at premium

## Summary
- Werth Family converted $5.8M debt/interest into 6.8M pre-funded warrants at $0.85/share (market $0.058).
- Phase 3 adult trial did not meet primary endpoint (PERMP over 16h, p=0.089) but showed trend and effect sizes 1.41 at 30min, 0.98 at 16h.
- CGI-S scores significantly improved (-1.2 vs 0.0, p<0.001); AISRS scores reduced by -16.3.
- Safety favorable: only one mild AE in CTx-1301 group vs three in placebo; no insomnia reported.
- NDA filing expected H2 2024; Phase 3 pediatric dose-optimization and fixed-dose trials ongoing.

## SEC filing metadata
- accession: 0001493152-23-032175
- form_type: 8-K
- ticker: CING
- cik: 0001862150
- company_name: Cingulate Inc.
- filed_at: 2023-09-11T23:59:59+00:00
- event_type: other_material
- sentiment: neutral
- materiality_score: 0.75
- calibrated_materiality_score: 0.75
- confidence: high
- sec_items: 1.01, 2.03, 3.02, 7.01, 8.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1862150/000149315223032175/0001493152-23-032175-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1862150/000149315223032175/form8-k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001493152-23-032175
- JSON: https://secwatch.observer/filing/0001493152-23-032175.json
- Plain text: https://secwatch.observer/filing/0001493152-23-032175.txt

## Key facts
- Material Agreements
  Cingulate Inc. entered into Note Conversion Agreement with Werth Family Investment Associates LLC (effective 2023-09-08).
  - Action: entry
  - Agreement: equity purchase
  - Counterparty: Werth Family Investment Associates LLC
  - Effective: 2023-09-08
  source text: On September 8, 2023, the Company and CTx entered into a Note Conversion Agreement (the “Note Conversion Agreement”) with WFIA, pursuant to which WFIA agreed to convert the Original Principal Amount under the A&R Note plus all accrued interest thereon, or $5,812,500, into pre-funded warrants (“Pre-Funded Warrants”) to purchase 6,838,235 shares (“Pre-Funded Warrant Shares”) of the Company’s common stock
  evidence_url: https://www.sec.gov/Archives/edgar/data/1862150/000149315223032175/0001493152-23-032175-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.